Objective To explore the position establishment and management methods of case managers in general hospitals, and to provide a reference for the management of patients from admission to 1 year after discharge. Methods Patients who underwent interventional therapy in the department of cerebrovascular disease were selected as the research subjects. A total of 121 patients treated from June 2021 to May 2022 were assigned to a control group without the management of case managers, and 120 patients treated from June 2022 to May 2023 were assigned to an intervention group with the management of case managers. The average length of stay, rate of on-time follow-up visits and medication compliance were compared between the two groups. Results Compared with the control group, the average length of stay in the intervention group was significantly shortened, and the rate of on-time follow-up visits was significantly improved (both P<0.05). There was no statistically significant difference in the unplanned readmission rate between the two groups （P>0.05）. Conclusion The position establishment of case managers is conducive to shortening the length of hospital stay of patients and improving the compliance with follow-up visits after discharge.