Objective To explore the current status of organizational silence and its influencing factors among senior clinical nurses, and to provide a basis for formulating targeted intervention measures. Methods A convenient sampling method was used to select 635 senior nurses from 3 tertiary A hospitals as the research subjects. A general information questionnaire, the Career Plateau Scale, and Nurses′ Organizational Silence Scale were used for the survey.Results The total score of organizational silence among senior nurses was (49.36±15.46). Gender, whether they had actively applied for additional practical opportunities to improve clinical skills, and career plateau were the influencing factors of organizational silence among senior nurses (all P<0.05). Conclusion Organizational silence among senior nurses is influenced by gender, practical opportunities, and career plateau, indicating that nursing managers should develop tailored intervention programs to reduce organizational silence in this group.