Objective To summarize the best evidence regarding oral nutritional supplements （ONS） for adult liver transplant reci-pients and to provide a reference for clinical nursing practice. Methods Based on the "5S" pyramid model of evidence-based information resources, relevant literature on ONS for adult liver transplant recipients was searched in domestic and international websites and databases.The search time limit was from the establishment of the database until June 2025.The methodological quality of the included literature was appraised, and the best evidence was summarized. Results A total of 13 documents were included, comprising 7 guidelines, 3 expert consensus statements, 2 systematic reviews, and 1 meta-analysis.Twenty-eight best evidence recommendations were summarized, covering 6 aspects:building multidisciplinary team, nutritional screening and assessment, selection of ONS products and nutrient ratios, pre- and post-operative ONS management, and discharge education. Conclusion The summary of best evidence for ONS management in adult liver transplant recipients provides an evidence-based reference for clinical nurses.Healthcare providers need to combine the clinical context and patient preferences to better apply and translate the evidence into practice.