Objective To explore the effectiveness of group mindfulness-based cognitive therapy (MBCT) in family caregivers of adolescents with depressive states, aiming to alleviate caregivers′ negative emotions and rebuild their psychological resilience resources. Methods A total of 60 family caregivers was recruited in the psychological counseling and treatment clinic and randomly assigned to either a control group (n=30) or an intervention group (n=30).The control group received immediate consultation and psychological support, while the intervention group additionally received an 8-week MBCT group intervention.Pre- and post-intervention measurements were conducted using the Depression-Anxiety-Stress Scale (DASS), the Connor-Davidson Resilience Scale (CD-RISC), the Five Facet Mindfulness Questionnaire (FFMQ), and the General Self-Efficacy Scale (GSES). Results Post-intervention, caregivers in the intervention group showed significantly lower scores on the DASS and higher scores on the FFMQ, CD-RISC, and GSES compared to those in the control group (all P＜0.05). Conclusion MBCT is beneficial in alleviating negative emotions and enhancing psychological resilience, mindfulness, and self-efficacy among family caregivers of adolescents with depressive states.