Objective To summarize the best evidence for fertility management in women of childbearing age with polycystic ovary syndrome (PCOS), and to provide evidence-based reference for fertility education. Methods Literature related to fertility management for women of childbearing age with PCOS was retrieved from websites and electronic databases from the establishment of the database to November 2024.Two researchers independently screened the literature, evaluated the quality of the included literature and extracted evidence. Results Fifteen publications were included, comprising 1 clinical decision support, 5 guidelines, 5 expert consensus statements and 4 systematic reviews.Thirty pieces of best evidence were summarized across six aspects:pre-pregnancy assessment and preparation, improvement of metabolism and ovulation, treatment of ovulatory dysfunction-related inferti-lity, pregnancy management and monitoring, timing and mode of delivery, and postpartum follow-up and long-term guidance. Conclusion The best evidence of fertility management for women of childbearing age with PCOS may serve as a reference for healthcare providers in delivering fertility education.Its application should be tailored to the individual needs and specific circumstances of each patient.