Abstract:Objective To summarize the relevant evidence on intraocular pressure (IOP) management in glaucoma patients, so as to provide an evidence-based basis for clinical IOP management in glaucoma. Methods A systematic search was conducted in domestic and foreign databases for evidence related to IOP management in glaucoma patients, including clinical decisions, guidelines, systematic reviews, evidence summaries and expert statements.The search period was from January 1, 2000 to May 1, 2025.Two researchers screened the literature, evaluated the quality, and extracted and integrated relevant evidence independently. Results A total of 11 literature were included, consisting of 4 guidelines, 5 systematic reviews, and 2 evidence summaries.Seventeen pieces of evidence were summarized across five aspects:IOP assessment, target IOP setting, medication guidance, healthy lifestyle education, and follow-up management. Conclusion Clinical staff need to apply the evidence in combination with actual clinical scenario and formulate IOP management strategies for glaucoma patients, so as to avoid excessive IOP fluctuations and delay disease progression.