Objective To develop an intelligent management system for monitor data and evaluate its preliminary application effect.Methods A multidisciplinary research team was formed to design the usage workflow of the system and to construct modules for data acquisition, data recognition, and back end supervision.The intelligent management system for monitor data was developed and preliminarily deployed in clinical settings.Outcomes before system implementation (May 2023-May 2024) were compared with outcomes after implementation (June 2024-June 2025), including alarm fatigue level, alarm response time, time required to update device quality inspection labels, and system usability satisfaction.Results After system implementation, alarm fatigue scores, alarm response time, and time to update device quality inspection labels were significantly improved compared with those before system implementation (all P＜0.05).Nursing staff reported high system usability satisfaction, with scores ＞4.50.Conclusion The intelligent management system for monitor data alleviates nurse alarm fatigue, improves alarm handling efficiency, and achieves high nursing staff satisfaction in clinical use.