Objective To comprehensively assess clinical application off all prevention and management evidence for inpatients, to develop audit indicators, to analyze barriers and facilitators, and to formulate action strategies. Methods Guided by the JBI′s approach to evidence implementation, an audit protocol was developed. A baseline audit was conducted to identify the barriers and facilitators in clinical practice, then targeted action strategies were formulated. Results Seven pieces of evidence were included, ge-nerating 8 audit indicators.The compliance rate was below 60.0% for four audit indicators and between 60.0% and 80.0% for three audit indicators. The main barriers to evidence-based nursing practice included: lack of specialty-specific characteristics in fall prevention protocols, deficiency of fall risk screening and assessment process, and poor awareness of patients and their families. Conclusion There is a gap between evidence and clinical practice in fall prevention and management for inpatients. Tailored action strategies with specialty-specific features should be adopted in different clinical contexts to facilitate the translation of evidence into practice.