Objective To identify latent subgroups of dyadic coping (DC) among bladder cancer patients with urinary diversion and their partners, and to explore the factors associated with these subgroups. Methods Convenience sampling method was utilized to select 223 pairs of bladder cancer patients with abdominal wall stoma for urinary diversion and their spousal caregivers. A general data questionnaire and the Dyadic Coping Inventory were given to the participants. A latent profile analysis of DC among bladder cancer couples was performed using Mplus 8.3. Predictors of profiles membership were identified using multinomial logistic regression analysis. Results The total DC score was ( 120.67 ± 11.84 ) in patients, and (125.28±12.45) in their partners. Participants were classified into four subgroups based on their DC levels: both high-DC group(30.9%), patient-low partner-moderate DC group (22.9%), both moderate-DC group (25.6%), and both low-DC group (20.6%). Marital relationship, patients′ and spouses′ education level, patients′ stoma self-care ability, time after stoma surgery and employment status were significantly associated with the four subgroups (all P<0.05). Conclusion There is considerable variability in DC levels among bladder cancer patients with abdo-minal wall stoma for urinary diversion and their spousal caregivers. Targeted interventions should be taken to the patient-low partner-moderate DC group and the both low-DC group.