Objective To evaluate and summarize relevant evidence on wearing compression sleeves in patients with breast cancer-related lymphedema, so as to provide a reference for standardized wearing of compression sleeves.Methods Following the "6S" evidence model, the evidence on wearing compression sleeves in patients with breast cancer-related lymphedema were searched from database inception to January 2025, the quality of literature was assessed, and the level of evidence were evaluated and summarized.Results A total of 17 articles were included, consisting of 2 best practices, 1 clinical decision, 5 guidelines, 1 expert consensus statement, 1 systematic review, and 7 randomized controlled trials.Totally 22 pieces of best evidence on wearing compression sleeves were summarized and categorized into 7 aspects:indications, contraindications, treatment plans, types of cuff wearing, pressure selection, daily monitoring and precautions.Conclusion The best evidence on wearing compression sleeves in patients with breast cancer-related lymphedema provides evidence for clinical practice, and medical staff should accurately evaluate and use according to the specific situation.