Objective To investigate the incidence and influencing factors of postoperativ esexual distress among gynecological cancer patients, so as to provide a reference for preventing and treating postoperative sexual distress. Methods A total of 282 patients undergoing gynecological cancer surgery were selected using a convenience sampling method, then they were investigated by using the Revised Female Sexual Distress Scale (FSDS-R), the Female Sexual Functioning Index (FSFI),the Dyadic Coping Inventory (DCI),the Revised Dyadic Adjustment Scale(RDAS),and the10-item Connor-Davidson Resilience Scale (CD-RISC-10). Logistic regression analysis was adopted to analyze the influencing factors of sexual distress. Results There were 122 patients experienced sexual distress, with an incidence rate of 43.26%. The participants′ score of the FSDS-R was 10.00(7.00,19.00). Logistic regression analysis showed that, the age at surgery, the ovaries were preserved or not,postoperative time,dyadic coping level,psychological resilience level and posto-perative sexual dysfunction or not were major influencing factors of postoperative sexual distress in patients with gynecological cancer (all P<0.05). Conclusion The incidence of postoperative sexual distress among gynecological cancer patients is high. It is necessary to take targeted interventions according to the influencing factors, enhance dyadic coping abilities between patients and their spouses, strengthen psychological resilience, so as to prevent the occurrence of postope-rative sexual distress.