Objective To search, evaluate and summarize the best evidence on the prevention of catheter related infection in adults on peritoneal dialysis (PD), and to provide guidance for clinical practice. Methods Evidence regarding prevention of catheter-related infection in adults on PD, including guidelines, expert consensus reports, clinical decision support statements, recommended practice statements, systematic reviews, meta-analysis and randomized controlled trials, was systematically searched in international and domestic databases from inception up to November 16, 2024. Methodological quality of the literature was evaluated indepen-dently by two researchers, and evidence was extracted, rated and summarized. Results A total of 10 publications met the inclusion criteria, including 3 guidelines, 3 expert consensus reports, 2 clinical decision support statements and 2 evidence summaries. A total of 20 pieces of evidence were summarized from 5 aspects including assessment, catheterization, daily care, education and training, and quality improvement. Conclusion The best evidence on catheter-related infection in adults living with PD can provide reference for clinical practice. It′s better to assess patient′s specific conditions to formulate personalized treatment regimen before evidence translation.