Objective To explore the posttraumatic growth (PTG) trajectories and their influencing factors in women undergoing termination of pregnancy due to fetal anomaly using latent growth mixture model(LGMM), and to provide references for formulating targeted psychological intervention strategies. Methods A total of 216 women undergoing termination of pregnancy due to fetal abnormalities were investigated using a general information questionnaire, the Chinese version of the Posttraumatic Growth Inventory, the Perceived Social Support Scale, and the Simplified Coping Style Questionnaire. Data were collected before termination of pregnancy, and at 2 weeks, 1 month, 3 months, and 6 months after termination of pregnancy. LGMM and multivariate logistic regression were used to identify PTG trajectories and their influencing factors. Results Two PTG development trajectories were identified:progressive growth group (66.2%) and fluctuating adaptation group (33.8%). Regression analysis showed that women with high social support and positive coping were more likely to be classified into the progressive growth group, while those with a history of abnormal pregnancy or those unemployed were more likely to fall into the fluctuating adaptation group (all P<0.05). Conclusion Women report lower PTG level in the early stage following termination of pregnancy due to fetal abnormalities, then their PTG development trajectories present considerable variability over time. Healthcare providers should design targeted intervention plans based on woman′s individual characteristics.