Objective To explore the effectiveness of adolescent epilepsy transition management based on the Information-Motivation-Behavioral Skills (IMB) model, and provide reference for the management of adolescent epilepsy patients during the transition period. Methods Adolescents with epilepsy admitted between October 2023 and March 2024 were selected as the research subjects and divided into an intervention group and a control group based on the time of enrollment, each consisting of 43 cases. The control group received conventional transition management, while the intervention group was managed using a transition program based on the IMB model. The intervention lasted for 8 weeks, followed by a 6-month follow-up. The levels of transition readiness and self-management efficacy were compared between the two groups. Results All 86 patients completed the entire study. After the intervention, the scores for transition readiness and self-management efficacy in the intervention group were significantly higher than those in the control group (both P<0.05). Conclusion The transitional management program based on IMB model can effectively improve the transition readiness and self-efficacy of adolescents with epilepsy.