Objective To explore the implementation effect of early bundle management in the emergency treatment of sepsis patients.Methods A total of 390 emergency sepsis patients were divided into a conventional group （183 cases） and an experimental group （207 cases） chronologically. The conventional group received the standard sepsis treatment model, while the experimental group implemented early bundle management for sepsis, including the establishment of a sepsis rapid response team, a septic shock resuscitation unit, and the development and application of a sepsis emergency module, etc.The treatment outcomes of the two groups were compared.Results The experimental group showed significantly shorter times for blood lactate measurement, fluid resuscitation, blood culture collection, antibiotic administration, vasoactive drug initiation, and hospital stay compared to the conventional group, and the mortality rate and hospitalization costs were significantly lower in the experimental group （all P＜0.05）.Conclusion Early bundle management can shorten the initiation time of emergency treatment, reduce the length of hospital stay, and lower the mortality rate and hospitalization costs for sepsis patients, then improve their treatment effect.