Objective To establish a quality-sensitive indicator system for intraoperative blood transfusion management and to promote the standardized development of safe intraoperative blood transfusion for surgical patients.Methods Based on evidence-based methodology and group discussions, a preliminary draft of the quality-sensitive indicator system for intraoperative safe blood transfusion management was established; then, through two rounds of expert consultation and analytic hierarchy process, the system and weights of quality-sensitive indicators were finalized.Results A quality-sensitive indicator system for intraoperative blood transfusion management was ultimately constructed, including 3 primary indicators, 7 secondary indicators, and 43 tertiary indicators.The response rate of experts in Delphi consultation was 100% for both rounds, with the authority coefficients being 0.888 and 0.898, and the coordination coefficients being 0.220 and 0.328, respectively (both P＜0.05).The following 3 indicators had the highest combination weights:the incidence of adverse reactions during intraoperative blood transfusion （0.073 1）, the accuracy rate of intraoperative blood transfusion records （0.073 1）, and the pass rate of intraoperative blood transfusion operation assessment （0.067 5）.Conclusion The quality-sensitive indicator system for intraoperative blood transfusion management is scientific and reliable, and can serve as an assessment tool for the continuous improvement of the quality of safe blood transfusion management for surgical patients.