Objective To explore the current status of death anxiety in patients with chronic heart failure (CHF) and to analyze its influencing factors. Methods A total of 301 patients with CHF were investigated using a general information questionnaire, the Death Anxiety Scale, the Self-Esteem Scale, the Herth Hope Index, and the Perceived Social Support Scale. Results The total death anxiety score in patients with CHF was (7.20±1.87) points, and 62.79% of the participants had high level of death anxiety. Multiple linear regression analysis showed that gender, age, heart function classification, self-esteem, hope, and perceived social support were factors influencing death anxiety, which could explain 55.3% of the total variance. Conclusion Patients with CHF report a high level of death anxiety. Medical staff should pay special attention to female, young, and those with poor heart function, and improve patients′ self-esteem, hope, and perceived social support levels, to reduce their death anxiety.