Objective To systematically evaluate qualitative studies on the home care experiences of caregivers for children with medical complexity, and to provide references for development of effective caregiver support programs.Methods Qualitative studies on the home care experiences of family caregivers for children with medical complexity were collected by searching databases including CNKI, VIP, Wanfang data, CBM, PubMed, Embase, CINAHL, PsycINFO, the Cochrane Library, and Web of Science.The search period extended from the establishment of databases to July 2024.The literature quality was assessed utilizing the JBI Criteria for Qualitative Research （2016）, and the findings were synthesized through Meta-integration approach.Results A total of 15 studies were included, yielding 50 themes from which 9 categories were summarized and 4 synthesis results were obtained:struggles and gains under the burden of caregiving, imbalances in family support, the need for enhanced community support, and overwhelming medical burdens.Conclusion Family caregivers for children with medical complexity face multiple dilemmas in home care.In the future, comprehensive healthcare services can be developed to support caregivers and their families through various avenues, including psychological support, professional guidance, and telenursing.These multifaceted approaches aim to effectively alleviate the caregiving burden, optimize the health management of pediatric patients, and enhance the overall well-being of families.