Objective To search and summarize the evidence relating to early screening and glycemic management of pancreatogenic diabetes, and to provide a guide for detection and effective management of pancreatogenic diabetes.Methods A systematic literature search was performed to identify relevant literature on screening and glycemic management of pancreatogenic diabetes across va-rious bibliometric databases, guideline websites, and websites of professional organizations and societies.The search time frame was from the inception of the database to May 31, 2024.Quality of the eligible literature was evaluated and evidence was extracted.Results Eighteen publications were included, involving 4 guidelines, 2 expert consensus statements, 1 evidence summary, 3 systematic reviews, 7 cohort studies and 1 case-control study.A total of 15 pieces of best evidence were summarized, covering 4 aspects:the purpose of screening, screening methods, glycemic control target, and glycemic management strategies.Conclusion The best evidence for early screening and glycemic management of pancreatogenic diabetes can provide a guide for medical staff.Howe-ver, the appropriateness and feasibility of each piece of evidence should be assessed by considering clinical situations before evidence translation into practice.