Objective To optimize the teaching contents and methods of the China Trauma Care Training-Nursing（CTCT-N）, and to improve the teaching effect.Methods According to the feedbacks and training needs of trainees, the CTCT-N project team optimized and upgraded the contents and teaching methods of the training program by literature review, group discussion and expert consultation, considering the role connotation and role function of trauma nurses.Online courses were provided, theoretical courses were updated, teaching workshops and appraisal contents were improved.A total of 911 nurses received theoretical teaching and workshop training of trauma care.After the training, the theoretical and skills tests and a satisfaction survey were conducted.Results A total of 798 nurses completed the test.The post-training theoretical test score was significantly enhanced (P＜0.05).The team-based workshop skills test score was （86.14±7.61）points.Trainees′ satisfaction with the training scored higher than 4.5 points.Conclusion The optimization of CTCT-N can enhance theoretical knowledge and trauma care skills of nurses, leading to sustainable development of trauma care training.