Objective To observe the clinical effect of horticultural therapy combined with intradermal acupuncture in improving liver-depression and fire-extinguishing type of generalized anxiety disorder.Methods A total of 159 patients with generalized anxiety di-sorder were randomly divided into horticulture therapy group, intradermal acupuncture group, and combined group, 53 cases each.All three groups were given traditional Chinese emotional care.On this basis, the horticulture therapy group was given conventional Chinese herbal horticulture treatment, the intradermal acupuncture group was given intradermal acupuncture treatment, and the combination group was given horticulture therapy combined with intradermal acupuncture treatment.All three groups were treated once a week for 8 weeks.Hamilton Anxiety Scale score, TCM syndrome score, Pittsburgh Sleep Quality Index score and serum indexes of the hypothalamic-pituitary-adrenal (HPA) axis were compared before and after treatment among the three groups.Results A total of 53 cases in the horticulture therapy group, 52 in the intradermal acupuncture group, and 51 in the combination group completed the study.In the 8th week of treatment, the scores of the Hamilton Anxiety Scale, TCM syndrome score, Pittsburgh Sleep Quality Index scale, and serum indexes of the HAP axis in the combination group were better than those in horticulture the-rapy group and intradermal acupuncture group (all P＜0.05).Conclusion Horticultural therapy combined with intradermal acupuncture can effectively improve the anxiety state and symptoms of traditional Chinese medicine, enhance the quality of sleep, and relieve hyperfunction of the HPA axis in patients with of liver-depression and fire-extinguishing type of generalized anxiety disorder.