Objective To explore the effects of a discharge preparation intervention program for pediatric patients operated for complex intestinal diseases.Methods A total of 108 pediatric patients operated for complex intestinal diseases in pediatric surgery and their primary caregivers were divided into 54 cases each in the control group and the intervention group according to the wards.The control group received routine perioperative care, while the intervention group received a discharge preparation intervention program in addition to the routine care.Results The discharge readiness scores for both the first and second hospitalizations in the intervention group were significantly higher than those in the control group.Additionally, the rate of unplanned readmissions after the first discharge was significantly lower in the intervention group (all P＜0.05).Conclusion Implementing a discharge preparation intervention program for pediatric patients operated for complex intestinal diseases and their caregivers helps improve family readiness for discharge and reduces the occurrence of unplanned readmissions.