Objective To explore the application effect of an intelligent call system in wards of hepatobiliary surgery department, so as to provide a reference for promoting the construction of intelligent call system in wards. Methods A total of 2,406 patients (120,449 times of call) admitted in wards of hepatobiliary surgery department from January to September 2022 were taken as a traditional call group,in which the traditional call system was used, and 2,676 patients (129,798 times of call) admitted in wards of hepatobiliary surgery department from October 2022 to June 2023 were regarded as an intelligent call group, in which an intelligent call system was utilized to realize accurate call, automatic call, quick response and other functions.Results According to the back end of the phone App, in the intelligent call group, the response rate was 92.0%, 432 times of leaving hospital abnormally were monitored, and 432 pieces of massages were automatically sent by the system to warn abnormal positioning of the patients; and 876 times of abnormal respiratory rate were detected, and 876 pieces of abnormal respiratory rate alarm messages were sent to nurse terminal; totally 639 times of abnormal heart rate were detected, and 639 pieces of abnormal heart rate warning messages were sent to the nurse terminal. The call response time of the intelligent call group was 4.52 (3.92,5.16)s, which was significantly shorter than that of the traditional call group ［51.52 (43.39,59.79)s ］; according to nurses′ appraisal, the accuracy performance score of the intelligent call system was 9 (8,9) points, which was significantly higher than that of the traditional call system ［5.5（1,10）points］(both P<0.05). Conclusion The intelligent call system is superior to the traditional call system in timeliness, accuracy and intelligence of call response, so it is conducive to realizing good communication in physicians, nurses and clients.