Objective To investigate the effect of "graduate-undergraduate mutual aid" learning workshop on cultivating nursing ta-lents with innovative ability.Methods A total of 34 second-year nursing graduates and 87 third-year undergraduate nursing students were recruited to participate in the "graduate-undergraduate mutual aid" learning workshop for 1 year, including theme-oriented learning and practice of nursing research.Self-directed learning ability, information literacy, research and innovation ability, and professio-nal nursing values of participants were measured before and after the intervention.Results Pre- and post-intervention scores for above-mentioned parameters had significant differences (all P<0.05).Conclusion The "graduate-undergraduate mutual aid" learning workshop can enhance self-directed learning ability, information literacy, research and innovation ability of nursing students, and boosts the formation of professional values.