Objective To determine the level and factors associated with self-disgust in clinical stage Ⅱ or Ⅲ low-rectal cancer patients with a stoma, and to provide reference for targeted intervention.Methods A total of 221 patients were invited to complete a battery of questionnaires, including a demographic questionnaire, the Questionnaire for the Assessment of Self-Disgust, the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being, the subscale of the Stoma Self-efficacy Scale (Stoma Care SE), and the Perceived Social Support Scale.Results The sample scored （33.52±8.40） for self-disgust.Multiple li-near regression analysis showed that stoma complications, spiritual health, stoma care self-efficacy and perceived social support were factors influencing self-disgust （all P＜0.05）, which could explain 83.6% of the total variance.Conclusion The self-disgust of low-rectal cancer patients with a stoma is at moderate to slightly high level.Nursing staff should provide targeted stoma care to prevent stoma complications, and improve patients′ spiritual health, stoma care self-efficacy, and social support, in an effort to decrease their self-disgust.