Objective To observe the effect of Traditional Chinese Medicine (TCM) rehabilitation nursing on limb function and quality of life of post-stroke hemiplegic patients. Methods A total of 108 post-stroke hemiplegic patients were selected and divided into a control group and an intervention group chronologically, with 54 cases in each group. The control group received routine rehabilitation nursing, while the intervention group additionally received TCM rehabilitation nursing, including sitting Baduanjin, herbal hot compress, massage, etc. Results After 3 months of intervention, there were a significant differences in limb motor function scores and quality of life scores between the two groups (all P<0.05). Conclusion Implementing TCM rehabilitation nursing for post-stroke hemiplegic patients can promote their limb function recovery and improve their quality of life.