Objective To investigate the effect of transanal irrigation (TAI) in patients with neurogenic bowel dysfunction (NBD) after spinal cord injury. Methods Totally 80 patients with NBD after spinal cord injury were divided into a control group and an experimental group in the order of hospitalization, with each group having 40 cases. The control group was given routine bowel management care while the experimental group was given TAI implemented by nurses using simple appliances on the basis of the control group. Results There were 39 cases completing the study in each group. After the intervention, the incidence rates of bloating, and defecation frequency score in the experimental group were significantly lower than those in the control group（all P＜0.05）. Conclusion TAI can significantly reduce such bowel dysfunction symptoms as bloating and abnormal defecation frequency in patients with NBD after spinal cord injury, and effectively improve bowel function.