Objective To investigate and analyze the current situation of career growth and its influencing factors in nursing managers, and oprovide a reference for hospital managers to take measures to enhance their career growth.Methods Nursing ma-nagers from 10 hospitals in Hubei, Shanxi, and Jiangxi provinces were selected.A cross-sectional survey was conducted using the general information questionnaire, the Career Growth Scale, the Nurse Manager Practice Environment Scale, the Perceived Stress Scale and the work-Family Conflict Scale, and the influencing factors were analyzed using multiple linear regression analysis.Results A total of 419 valid questionnaires were collected.The career growth score of nursing managers was （59.63±9.10） points.The career growth was positively correlated with practice environment, and negatively correlated with perceived stress and work family conflict （both P＜0.05）.Multivariate regression analysis showed that career satisfaction status, adequate human and material resources, building a safe cultural environment, relationship with physicians, and behavioral conflicts were factors influencing career growth of nursing managers.Conclusion The score of career growth in nursing managers was at a relatively high level, and hospital managers should develop intervention strategies to further enhance career growth of nursing managers by enhancing their career satisfaction, improving their professional practice environment, and reducing behavioral conflicts.