Objective To evaluate the application effect of wearable devices in home rehabilitation care for patients after anterior cruciate ligament reconstruction surgery. Methods According to the time of admission, a total of 33 patients who underwent anterior cruciate ligament reconstruction surgery in the department of osteoarthritis from January to June 2022 were selected as a control group, and 31 patients from July to December 2022 were selected as an experimental group. The control group received routine rehabilitation training. The experimental group received routine rehabilitation while wearing wearable devices based on sensors for home rehabilitation supervision and guidance. The patients′ knee function scores and rehabilitation exercise compliance scores were evaluated at 2, 6, and 12 weeks postoperatively. Results The scores of Lysholm knee joint, IKDC, and rehabilitation exercise compliance were statistically significant between two groups in terms of time effect, inter-group effect, and interaction effect (all P<0.05). Conclusion Wearing sensor-based wearable devices for home-based rehabilitation supervision and guidance can effectively improve patient rehabilitation exercise compliance, and knee joint function of patients after anterior cruciate ligament reconstruction surgery.