Objective To construct a nursing intervention programme for peritoneal dialysis patients based on the emotional intelligence model, and explore its application effects. Methods The admitted peritoneal dialysis patients were divided into an intervention group and a control group by ward, with 35 cases in each group. The control group implemented routine nursing care, and the intervention group additionally received the nursing intervention program based on the emotional intelligence model, intervening once a week for 7 weeks. Emotional intelligence, social alienation, and perceived social support scores were evaluated before and after the intervention in both groups. Results Thirty two cases in the intervention group and 33 cases in the control group completed the study. The scores of emotional intelligence, and perceived social support were significantly higher, and the score of social alienation was significantly lower in the intervention group than in the control group after the intervention (all P<0.05). Conclusion The nursing intervention program based on the emotional intelligence model can improve peritoneal dialysis patients′ emotional intelligence, alleviate social alienation, and enhance perceived social support,which is conducive to enhancing their physical and mental health.