Objective To construct a hospice care question prompt list and provide a relevance to surrogate decision makers for advanced cancer patients proactively access hospice care related information. Methods From January to August 2023, the information need themes and corresponding entries of surrogate decision makers for patients with advanced cancer were summarised through a literature review and semi-structured interviews. The study optimised the content of the question prompt list through 2 rounds of expert correspondence with 20 experts and pre-surveys. Results The final question prompt list of hospice care for surrogate decision makers in advanced cancer patients included 7 primary items and 44 secondary items, covering topics such as hospice care, treatment decision-making, symptom management, end-of-life preparedness, decision-making aids, psychological and emotional support, and social support. Conclusion The constructed hospice care question prompt list is comprehensive and reliable. It can help surrogate decision makers obtain the necessary information about hospice care and decision-making, and reduce decision conflicts and delays that they may face in the hospice care decision making process.