Objective To explore the effect and safety of inhaling compound sachets of Chinese herbal medicine on alleviating dysme-norrhea related to cold coagulation and blood stasis in college students.Methods A total of 100 college students suffering from dysmenorrhea related to cold coagulation and blood stasis were divided into a control group and an experimental group using stratified randomization method, with 50 students in each group.Health education was provided to both groups, and the control group also received placebo sachet inhalation, while the experimental group inhaled compound sachets of Chinese herbal medicine for three menstrual cycles, each night while sleeping, hang the sachet on the side wall at 30 cm from the participants′ nose.Results Totally 46 students in the control group and 48 students in the experimental group completed the study.After the intervention, there were significant differences in the score of the abdominal pain Visual Analogue Scale (VAS), the Cox Menstrual Symptom Scale (CMMS), the Pain Catastrophizing Scale (PCS) and the treatment efficacy between the two groups (all P＜0.05).During the study, no adverse reactions were reported in the two groups.Conclusion Inhaling compound sachets of Chinese herbal medicine is conducive to alleviating abdominal pain, relieving symptoms of dysmenorrhea, and reducing pain catastrophizing in college students suffering from dysmenorrhea related to cold coagulation and blood stasis.