Objective To explore the implementation effect of chain management led by specialized stoma nurses in pediatric patients with temporary stoma, in order to promote the comprehensive management and early postoperative recovery in children with temporary stomas. Methods Based on hospitalization periods, pediatric patients with enterostomy were divided into a control group and an experimental group. The control group, comprising 32 cases admitted from June 2020 to June 2021, received routine nursing care. The experimental group, consisting of 32 cases admitted from July 2021 to June 2022, implemented chain management led by specialized stoma nurses at three stages:the initial stoma period, home-based health care period, and stoma return period. Results The experimental group showed no statistically significant differences in the incidence of postoperative stoma-related complications and unplanned hospitalization rates compared to the control group (all P>0.05). However, the satisfaction score of caregivers was significantly higher in the experimental group than that in the control group (all P<0.05). Conclusion The implementation of chain management led by specialized stoma nurses for pediatric patients with enterostomy has realized comprehensive care, optimized the medical process, and may relatively reduce the incidence of postoperative stoma-related complications, improve caregiver′s satisfaction, thereby promoting early recovery in pediatric patients.