Objective To systematically sort out the frameworks or models for assessing the implementability of clinical practice guidelines at home and abroad , and to provide methods and reference for the development as well as implementation of domestic guidelines. Methods We systematically searched PubMed, Web of Science, EMbase, China Knowledge Network (CNKI), Sinomed, Wanfang Database, BMJ Best Practice, UptoDate, the Cochrane Library, Medlive, National Guidelines Corporation (NGC), and National Institute of Clinical Medicine Guidelines Library (NICE), and supplemented with searches of Shiffman RN and Gagliardi AR. The search time frame was limited from January 1, 2012 to August 31, 2023. Results Twenty-six full-text articles were ultimately included:8 content descriptions of the frameworks/models and 18 clinical applications of the frameworks/models. Six frameworks/models were included: the Guideline Implementability Framework, the Guideline Implementability Tool (GUIDE-IT), the Guideline Implementability Appraisal (GLIA), the Guideline Implementability Decision Excellence Model (GUIDE-M), the Guideline Language and Format Instrument (GLAFI), and the Checklist for Guideline Implementation Planning. Conclusion The application of a rational framework or model in guideline development and implementation can increase the efficiency of guideline implementation. Guideline implementability frameworks or models need to strike a balance between comprehensiveness and implementation, and validation and refinement of existing tools are needed in the future. Professional implementation researchers should be actively involved in specific implementation processes to facilitate guideline implementation and promote its continued application in practice.