Objective To explore the effects of family integrated care (FICare) model on the growth and family care ability for premature infants. Methods A total of 74 premature infants with pregnancy weeks .< 37 weeks were selected as research objects,and randomly divided into 2 groups of 37 cases each. The control group received routine nursing care of premature infants. The intervention group received integrated care for preterm infants based on FICare model, with a team of neonatal nurses providing integrated care support at birth, after birth and after discharge. The growth and development, breastfeeding and family care ability of premature infants were compared between the two groups. Results A total of 36 cases in each group completed the whole follow-up. There were no significant differences in body length, body weight and head circumference between the two groups at birth, 1 month and 3 months of age (all P>0.05). The rates of exclusive breastfeeding before discharge, at 1 month and 3 months of age in the intervention group were significantly higher than those in the control group, and parents in the intervention group had signi-ficantly higher scores family care ability at discharge (all P.<0.05). Conclusion The FICare model for premature infants can effectively promote exclusive breastfeeding for premature infants, improve care ability of the infants′ families, and provide a favorable guarantee for the smooth transition of premature infants from birth to the external environment after discharge.