Objective To develop a novel prenatal "3-PR" participatory health education model and to evaluate its clinical effect.Methods A total of 120 pregnant women hospitalized for childbirth were assigned to a control group or an observation group chronologically, with 60 in each.The control group received routine health education, while the observation group additionally received prenatal "3-PR" participatory health education. Family members in both groups were asked to participate in the education.Effects were evaluated before discharge.Results The score and incidence of anxiety were significantly lower, whereas the breastfeeding rate and the score of skills in caring for the neonate were significantly higher in the observation group compared with the control group （all P＜0.05）.Conclusion Implementing prenatal "3-PR" participatory health education is helpful to relieve maternal anxiety, improve breastfeeding rate and neonatal care skill.