Objective To test the reliability and validity of the Chinese version of Spiritual Coping Questionnaire (SCQ) in nursing students, and to provide a tool for assessing spiritual coping strategies of nursing students. Methods The Chinese version SCQ was used to survey 1 584 nursing students in 2 universities in terms of their spiritual coping strategies.Two weeks later, a class (93 students) was randomly selected for retest. Results The Chinese version SCQ has 26 items and 2 subscales:the positive spiritual coping subscale includes three dimensions (personal, environmental and transcendental), while the negative spiritual coping subscale only has one dimension.The cumulative variance contribution rate of the four common factors was 66.885%.Confirmatory factor analysis showed that the goodness-of-fit indexes of the were as follows:four-factor model fitted well χ2/df=5.783,TLI=0.891,CFI=0.903, and RMSEA=0.078.The Cronbach′s α coefficient for the overall scale stood at 0.887, the Guttman split-half coefficient was 0.940, and the test-retest reliability coefficient was 0.961. Conclusion The Chinese version SCQ has good reliability and validity and can be used as an effective tool to assess spiritual coping strategies of nursing students in China.