Objective To construct a rehabilitation program based on exercise risk stratification for patients undergoing cardiac pacing therapy, and to evaluate its application effect. Methods A total of 108 patients undergoing cadiac pacing therapy were divided into 2 groups of 54 cases each according to the time of admission by convenient sampling method. The control group was guided to performed routine activities, while the intervention group was subjected to a rehabilitation program based on exercise risk stratification on the basis of routine activities.On the first day after operation and before discharge, the scores of exercise fear （TSK-SV Heart）, the Disabilities of the Arm,Shoulder and Hand questionnaire （DASH）, Duke Activity Status Index（DASI） and Self-Efficacy for Symptom Management Scale （SESMs） were evaluated. Results At last, 49 patients in the control group and 53 patients in the intervention group completed the study. After intervention, the scores of exercise fear, upper limb function, Duke Activity Status Index and self-management efficacy in the intervention group were significantly better than those in the control group （all P＜0.05）. Conclusion Rehabilitation program based on exercise risk stratification for patients after cardiac pacing therapy can alleviate patients′ fear of exercise, improve functional status of the upper limbs, and enhance patients′ physical activity level and self-management efficacy.