Objective To explore the application effect of work method by WeChat mini program in the home extended care of patients with dysphagia after stroke, and to provide new ideas and methods for the home extended care of patients with chronic diseases. Methods Forty-three patients with dysphagia after stroke admitted to hospital from January to June in 2021 were set as the control group, and 46 patients admitted to hospital from July to December in 2021 were set as the observation group. The control group was followed up after discharge, while the observation group was followed up by WeChat app. The incidence of complications of eating at home, and the compliance of rehabilitation exercise in the two groups within one month after discharge were compared, and the swallowing function of the patients in the two groups was evaluated one month after admission and discharge. Results The difference of SSA scores between the two groups 1 month after discharge was statistically significant (P<0.05); the incidence of complications of home eating between the two groups within 1 month after discharge was statistically significant (P<0.05); the scores of 3 dimensions of the rehabilitation exercise compliance scale in the observation group were higher than those in the control group within 1 month after discharge, and the difference was statistically significant (P<0.05). Conclusion The application of work method by WeChat mini program in home extended care for patients with dysphagia after stroke can significantly improve the swallowing function of patients, reduce the incidence of complications of home eating, and improve the compliance of patients participating in rehabilitation therapy.