Objective To translate the Exercise Sensitivity Questionnaire into Chinese and test its reliability and validity in patients with cardiovascular diseases. Methods After obtaining authorization from the original author, the Chinese version of Exercise Sensitivity Questionnaire was formed after translation, back translation and cultural adaptation. A total of 499 inpatients in the department of cardiology were surveyed, and the reliability and validity of the scale were tested. Results The I-CVI and S-CVI of the Chinese version were 0.830-1.000 and 0.924, respectively. Exploratory factor analysis extracted two common factors, and the cumulative variance contribution rate was 65.005%. The results of confirmatory factor analysis were as follows:χ2/df=2.570, RMSEA=0.056, NFI=0.964, IFI=0.978, TLI=0.973 and CFI=0.978. The Cronbach′s α coefficient, split-half reliability and test-retest reliability of the scale were 0.984, 0.985 and 0.932, respectively. Conclusion The Chinese version of Exercise Sensitivity Questionnaire has good reliability and validity. It can be used as a tool for assessing exercise perception of patients with cardiovascular diseases.