Objective To summarize the best evidence for management of transition from pediatric to adult healthcare in patients with type 1 diabetes mellitus （T1DM） and to provide references for tansitional care. Methods According to the "6S" pyramid evidence model, the computer decision support systems, guideline websites, professional academic websites and databases were searched for literature related to management of transition from pediatric to adult care in patients with T1DM, in an effort to retrieve evidence from guidelines, evidence summaries, best practice information manuals, clinical decision, expert consensus, systematic reviews and randomized controlled trials （RCTs）. The retrieval time was from the establishment of databases to August 31, 2022.The quality of the included literature was evaluated and graded. Results A total of 19 pieces of literature were eligible for inclusion. They were 1 clinical decision report, 4 guidelines, 6 expert consensus reports, 7 systematic reviews and 1 RCT. Totally 22 pieces of best evidence were summarized from 4 aspects of general principles, transition preparation, care transfer, and integration into adult health care. Conclusion Pediatric and adult healthcare providers should conduct a comprehensive analysis of patients with T1DM during the care transition period, and select targeted evidence, so as to formulate a heath care transition management program for patients with T1DM that meets individual conditions. Transition programs for patients with T1DM facilitate their transition from pediatric to adult care, and improve their transition experiences and health outcomes.