Abstract:Objective To review the literature on symptom clusters in lung transplant recipients, and to provide reference for symptom management. Methods Nine domestic and international electronic databases were searched from database construction until 10 March 2022. The studies regarding symptom clusters in patients after lung transplantation were retrieved according to the eligibility criteria. Results Finally, 11 studies were included, and 9 symptom clusters were extracted. The top 3 symptom clusters in frequency were psychological, neuromuscular, and gastrointestinal. Tools used in these studies for assessing symptoms were categorized into two types:single-symptom and multi-symptom assessment tools. Factors affecting symptom clusters were sex, adverse effects of immunosuppressant drugs, and coexisting disease, etc. Conclusion Symptom clusters in lung transplantation patients change over time and are affected by many factors. Specific measurement tools need to be developed.