Objective To explore the management efficiency of a packaged management and control platform for disposable low-value consumables in operating room. Methods A design of historical control trial was utilized, totally 17,522 operations were performed in the operating room from May to December 2019 (before precise management and control), the low-value consumables were routinely managed; and a total of 15,447 operations were completed from May to December 2020 (after precise management and control), while the low-value consumables were precisely controlled, including development of a packaged management and control platform for disposable low-value consumables according to the characteristics of various specialties in the operating room, and precise management for low-value disposable consumables. Results After the precise management and control of the low-value consumables, the weekly inventory inspection time and sporadic application times were significantly lower than those before the precise management (P<0.01 for both), and there were significant differences in disposable low-value consumables inventory accumulation and standard rate of consumables placed in expiry date when compared with those before the precise management and control (P<0.01 for both). Conclusion Implementation of packaged and precise management and control of disposable low-value consu-mables in operating room, is benefit for dynamic management of low-value consumables, improving the management quality of low-value consumables, and reducing inventory accumulation and loss.