Objective To reduce the incidence of postoperative nausea and vomiting in patients undergoing pulmonary surgery. Methods A prospective non-contemporaneous control design was adopted. Eighty-six patients hospitalized in July 2020 for pulmonary surgery were enrolled into a control group, who were managed using routine method for pulmonary surgery, then their 87 counterparts hospitalized in September 2020 were divided into an intervention group, and special management using feed-forward control was adopted for postoperative nausea and vomiting. Results The incidence of nausea and vomiting after pulmonary surgery in the intervention group was significantly lower than that in the control group (P<0.05). Conclusion Application of feed-forward control for postoperative nausea and vomiting management in patients undergoing pulmonary surgery, can reduce incidence of postoperative nausea and vomiting and facilitate rapid recovery.