Objective To construct a multidisciplinary nutrition management scheme for malnourished patients undergoing lung transplantation, and to explore its application effect on nutritional status and rehabilitation after transplantation for preoperative malnourished patients. Methods The malnourished patients before lung transplantation were divided into a control group (n=49) and an intervention group (n=50) chronologically.The control group was given routine nutrition management,while the intervention group received multidisciplinary nutrition management scheme including exercise prescription, nutrition prescription, drug therapy, psychological management, etc. Results One month after the lung transplantation, the total albumin, albumin, erector spinal muscle cross-sectional area, 6-Minute Walk Distance and modified Medical Research Council score of the intervention group were significantly better than those of the control group, and its postoperative hospital stay was significantly shorter than that of the control group (P＜0.05,P＜0.01). Conclusion Multidisciplinary nutrition management is conducive to improving the nutritional status after lung transplantation for preoperative malnourished patients, and promoting their rehabilitation.