Objective To translate and culturally adapt the Coping with Death Scale (CDS）, and to test its reliability and validity among oncology nurses. Methods The CDS was translated into Chinese and back-translated following the guideline of Brislin translation model. Then, the translated scale was further revised based on the results of expert review and pilot study. Finally, a total of 446 oncology nurses from five tertiary cancer hospitals across Mainland China were recruited to test the reliability and validity of the Chinese version CDS. Results The revised simplified Chinese version CDS included 28 items which were grouped into 6 factors.S-CVI of the scale was 0.987, and I-CVIs were between 0.832 to 1.000.Six factors enjoyed a cumulative contribution rate of 60.800%.The Cronbach′s α coefficient for the Chinese version CDS was 0.905, the Guttman split-half reliability was 0.784, and the test-retest reliability of the scale was 0.973. Conclusion The simplified Chinese version CDS has good reliability and validity. The scale can be used to assess oncology nurses′ capability of coping with death.