Objective To retrieve, assess and summarize the existing evidence on fluid management in maintenance hemodialysis patients. Methods Systematic searches for evidence were performed across multiple sources as electronic databases and websites, to retrieve clinical decision, guideline,evidence summary,best practice information sheet,recommended practice,expert consensus and systematic review on fluid management in maintenance hemodialysis patients. Results Two best practice reports, 6 guidelines, 1 expert consensus statement, 2 evidence summaries and 1 systematic review were included. Four aspects with 14 pieces of evidence were summarized, including assessment and monitoring, sodium and fluid restriction, management of volume overload and enhancing patient compliance. Conclusion Medical staff could implement the evidence into clinical practice by considering situation of the institution and patient′s preference, thus to develop patient-centered fluid management protocol and improve nursing quality.