Objective To explore the cutoff values of intravesical pressure in prediction of upper urinary tract injury in patients with spinal cord injury. Methods Retrospective analysis of medical records of 97 patients with spinal cord injury was conducted. The patients were divided into an injury group and a non-injury group in accord with the diagnosis standard of injury to upper urinary tract. The baseline data of the two groups were compared, and an ROC curve was drawn by comparing intravesical pressure results to diagnosis results of injury versus non-injury. Results The injury group was older in ages, and had shorter course of disease than the non-injury group （P<0.01 for both）. According to the ROC curve, the optimal cutoff value of intravesical pressure was 33.25 cmH2O. Conclusion An intravesical pressure of 33.25 cmH2O could predict upper urinary tract injury in patients with spinal cord injury.