Objective To explore the effects of coloring mandalas on benefit finding in family caregivers of cancer patients. Methods Eighty family caregivers of cancer patients were divided into a control group and an experimental group of 40, receiving either conventional health education or 8 sessions of coloring mandalas. Before and after the intervention, the effect was evaluated by the revised Chinese version of the Benefit Finding Scale. Results The total score of benefit finding in the experimental group was significantly higher than that in the control group after 4 weeks of intervention (P<0.05). Conclusion Coloring mandalas can improve benefit finding of family caregivers of cancer patients, thus to promote their physical and mental health.