Objective To explore the effect of precise aid program to ICUs of secondary hospitals on the core competence of intensive care nurses in primary hospitals. Methods A help group was set up to precisely deliver aids to the intensive care units of three secondary hospitals in Hainan Province. According to needs assessment, a help plan was formulated and implemented to enhance the core competence of intensive care nurses in the 3 primary hospitals. Results The total competence scores of the ICU nurses in the three secondary hospitals averaged 355.73±41.41 (before aids) and 355.73±41.41(after aids), respectively, and there was statistical difference in before-after measurements（P<0.01 for all）. There were statistical differences in the before-after scores of professional knowledge and skills, patient safety and rights, professional ethics, teamwork and individual and professional development（P<0.01 for all）. After aids, nurses also scored significantly higher in theory, and skill exams than before aids, and the rate of nurses reaching target scores improved significantly from before（P<0.01 for all）. Conclusion Precise aid to ICUs of secondary hospitals has a positive effect on the improvement of core competence of intensive care nurses in primary hospitals.